February 24, 2006
Systems Analytics Signs CRADA with U.S. Army
A Cooperative Research and Development Agreement (CRADA) between U.S. Army Center for Environmental Health Research (USACEHR) and Systems Analytics Inc. was approved on February 24, 2006. This CRADA has a title “Software Development for Systems Biological Integration of Proteomic and Genomic Data”.
The mission of the USACEHR is to enhance Force Health Protection by developing biologically based risk assessment products. The Laboratory has commenced research to broadly screen for novel measurable molecular or biochemical alterations (biomarkers) in biological matrices, such as fluids, cells, or tissues that occur in response to hazardous chemical exposure. Since biomarkers can indicate the degree of exposure, biological effects, and susceptibility to disease from toxic hazards, they have many potential applications in Force Health Protection and health surveillance.
Under the term of this agreement, Systems Analytics will develop efficient and robust methods and algorithms for data reduction and mining, and statistical tools for comparing samples to identify changes in gene or protein expression levels that indicate good biomarkers. Moreover, the company will develop innovative methods for comparing the results of gene (microarray) and protein expression (MS) experiments and integrating them into a cohesive, systems biology representation of the interactions and interrelations between gene and protein expressions.