April 29, 2005

Systems Analytics Receives SBIR Phase I Award from U.S. Air Force for Developing Bioinformatics Software for Proteomics Studies

Needham, MA -- The Air Force has awarded Systems Analytics, Inc. an SBIR Phase I research grant to develop an innovative bioinformatics software to aid in the analysis and interpretation of proteomics data. The software is capable of quantifying and interpreting complex and time-dependent global changes in various biological data profiles. It will identify the links between protein expression changes with upstream and downstream events in the context of biological pathways. Protein expression and post-translational modification data will be used to identify protein expression changes. The proteomics data will be integrated with gene expression data and metabolomics data to identify the molecular events up- and down-stream of these protein changes in the pathways involved in the cellular response to the external insults.

The developed bioinformatics software will have both military and civilian applications. For example, it can be used by the military to monitor health status of deployed personnel and to detect and diagnose exposure to physical, chemical and biological stressors, so that appropriate deployment decisions can be made. The software can also be used by the homeland security to monitor and detect suspicious terrorist activity and implement emergency response plans. In the private sectors, it can be used by biotechnology and pharmaceutical companies to identify new biomarkers, by environmental conscious organizations to assess and monitor effects of low-level intakes of toxic materials, and by the health care industry to monitor and assess the effectiveness of treatment, diet and fitness activities.

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